Anyone know of a resource that layouts the temporal activation patterns for all the genes for the life cycle of a human being?
0. https://portal.hubmapconsortium.org/ 1. https://data.humancellatlas.org/
The NIH BRAIN initiative is working on the next generation of that, covering more timepoints and better spatial data.
> Not sure what type of chart you're looking for. Just geek curiosity.
Oh no…
As someone who has an highly irregular sleeping pattern, do you know of any or where I can find more info on this?
> It's not an obvious problem in lots of ways.
Care to expand on this?
Link for others:
https://www.science.org/doi/10.1126/science.abl4896
https://maayanlab.cloud/Harmonizome/dataset/Tabula+Sapiens+G...
You may also like GTEX and the Human Protein Atlas (which also has gene expression data)
And if we ran an experiment where we gave it to some apes…
wikipedia tells me they are machines, but not what they're made of
Really, the likelihood is that these mutations must have had an impact that far outweighs their space in the genome.
That’s how all our close competition got murdered by Homo Sapiens. Just significant difference in mental abilities.
I think its rather some mutations that produced more reelin and created the most successful animal in earth's history
The testes are dangerously exposed, the plumbing is convoluted and failure-prone (and doesn’t recover well from mechanical insults).
The prostate, which serves no function outside of reproduction, lies inline with the urethra and quite consistently loses flexibility and becomes enlarged with age, causing all sorts of structural issues impacting basic urological function.
Female reproductive vs urinary anatomy is largely physiologically distinct (proximity and UTI risk notwithstanding). Though plenty of room for improvement there too — starting with endometrial tissue being far too prolific. Fun fact: endometrial tissue can migrate to the brain and cause haemorrhaging in severe cases of endometriosis.
Plenty of room for improvement across the board, I’d say!
aaand we have Quake and Comand&Conquer - Red Alert
Agreed, it would seem that evolutionary biology peaked in the late 90s then
Has another animal proposed they are more successful by a different metric?
Crickets?
To who? Other humans?
It's seagull mating season where I am, and I don't speak seagull, but I'm pretty sure one of the things they're trying to convey to their fellow seagulls is that they're extremely successful.
Can't argue with it either. They're very much alive, which is the best you can be in this particular competition.
Really interesting article though. I’m very hopeful AI can help work out how all these things interact.
That's not an explanation, you just replaced a problem with another harder one.