This looks neat, but if encoding/decoding performance is important, payload size isn't and the integer is bounded, I would just put a fixed-size integer into the payload as-is.
LEB128 (and JSON for that matter) can encode integer values of arbitrary length. This doesn't, which may or may not be important but it's different.
I'll admit that I do not do any cryptographic work with my library and therefore canonical representations aren't a huge concern in my use-cases. I merely provide various configurable limits (max value length, max depth, max items per collection) to prevent infinitely long documents from hogging my tokenizers indefinitely.
The upsides: the size of the integer is apparent upon reading the first byte, and every number has exactly one canonical representation. I wish C strings had been standardized around something similar, instead on null termination.
> ...adversarial input, which is rarely in the test suite.
This made my scratch my head. My tests for quite pedestrian APIs often contain adversarial input of obvious shapes. I though that for anything security-related (like the author's project) testing against adversarial input would be be a prominent part.
The downside is the encoding size. LEB128 quickly grows to 2 bytes, but stays at 2 bytes all the way to 2^14. This is important if you're using these numbers as tags/identifiers as we were in the multicodec [1] project, or for network message lengths. bijou64 only gives you 500 <= 2 byte numbers.