I'd suggest the Datapoint 2200 as the most influential minicomputer of all time since half of you are using an instruction set based on it and it is largely responsible for the creation of the microprocessor.

Now mostly forgotten, the Datapoint 2200 was a programmable desktop computer introduced in 1970. It had a processor built from TTL chips, along with shift-register memory from Intel. Datapoint discussed with Intel and Texas Instruments the possibility of building a single-chip processor to replace the board of TTL chips. TI was first with the TMX 1795 processor, followed by Intel's 8008, both copying the Datapoint 2200 instruction set.

Datapoint decided that these chips didn't have enough performance and fatefully gave up rights to them. TI tried to sell the TMX 1795 to Ford, but got nowhere and abandoned the chip. Intel decided to sell the 8008 as a standalong microprocessor, which was used in early personal computers like the Mark-8. Intel improved the 8008 to form the 8080, then made a somewhat compatible 16-bit version, the 8086, which started the x86 architecture. (Because the Datapoint 2200 was little-endian (to use shift-register memory), x86 is little-endian.)

To summarize its influence, without the Datapoint 2200, the microcomputer industry would have been greatly delayed (since the 4004 wasn't suitable for a personal computer) and x86 wouldn't exist.

It was the preferred lab computer in the mid to late 1970s and into the 80s. I got my first job because I knew PDP-11 assembly language, and worked with both DEC's operating systems for them (RT-11 and RSX-11) and later Unix (the lab I worked with had some machines running Version 6, though Version 7 was the first that I used seriously. It had a very clean and symmetric instruction set that used the program counter as if it were another general purpose register. I had an LSI-11 board (the single-board version of the machine) with 4K 16-bit words of core memory and a paper tape punch with a tiny loader in ROM to read in the tape and peek and poke memory, and I'd sometimes initialize the core memory to a known state by running the one-instruction program

mov -(pc), -(pc) or 014747 in octal. It would fill all of memory with 014747.

I'd argue the pdp8 opened the floodgates. That's when the cost of digital computing dropped to the point a research grant or even just discretionary spending in a university department could pay for one, and you didn't need a special room and power supply.

the 11 was when it became more useful. But the 8 was how people realised you could move beyond a calculator to a computer.

There's a parallel worldline out there where the PDP-11 made the transition into a desktop PC[0] and the IBM PC didn't take over the world. In that worldline our servers are from the PDP-11 lineage, and not the IBM PC.

[0] https://en.wikipedia.org/wiki/DEC_Professional_(computer)

"PDP-11 with UNIX opened the floodgates for inexpensive interactive computing, which then led to an explosion of office productivity. "

Well before we get too misty eyed: "inexpensive" needs looking at "for inexpensive interactive computing".

I'm not old (55) enough to have really got to grips with a PDP11. I do still own (yes: present tense) a C64 from 1986. The C64 was bought by my dad via the NAAFI in West Germany so I have no idea what it costed. Let's wind forward a bit:

I had a 80286 based PC in 1987ish with 1MB of RAM, 20MB RLL hard disc. The graphics card (ISA) had a whopping 512 bytes of RAM. That thing costed about £1200. I added a 80287 later at about £120 so I could run a pirated copy of AutoCAD.

In 1990ish I had a 80486 with 4Mb RAM and 40MB HD - that costed something like £1600.

Nowadays £1600 will buy quite a decent laptop and 35 years of inflation.

I had a PDP-11, in the form of the Heathkit H-11.

I loved that computer. Like a fool, I sold it for $25. There's a picture of it on my X profile.

The -11 had an instruction set that fit on one page.

+1 to pdp11. The workhorse of the 1970's. They were everywhere. City Library. Auto parts stores. And reliable; Maytag ain't got nothing on a pdp 11.

Downside, programs are pretty simple that run in 64k. And extended addressing in any form, sucks.